/test.data/ruleCompressions/model/quantitative/~kappa014.test

http://github.com/kappamodeler/jkappa · Unknown · 45 lines · 44 code · 1 blank · 0 comment · 0 complexity · 09e38d7a7aea0ad39fd4e0d2913ffff5 MD5 · raw file 

    

  1. # Rules:

    2. 

  2. #######

    3. 

  3. # Chapter 'Chapter 1'

    4. 

  4. 'Ras_Raf' Ras(S1S2~gtp),Raf(x~u) -> Ras(S1S2~gtp!1),Raf(x~u!1) @ 1.0

    5. 

  5. 'Raf' Ras(S1S2~gtp!1),Raf(x~u!1) -> Ras(S1S2~gtp!1),Raf(x~p!1) @ 1.0

    6. 

  6. 'Ras_Raf_op' Ras(S1S2~gtp!1),Raf(x!1) -> Ras(S1S2~gtp),Raf(x) @ 1.0

    7. 

  7. 'PP2A1_Raf' PP2A1(s),Raf(x~p) -> PP2A1(s!1),Raf(x~p!1) @ 1.0

    8. 

  8. 'Raf_op' PP2A1(s!1),Raf(x~p!1) -> PP2A1(s!1),Raf(x~u!1) @ 1.0

    9. 

  9. 'PP2A1_Raf_op' PP2A1(s!1),Raf(x!1) -> PP2A1(s),Raf(x) @ 1.0

    10. 

  10. # 'Raf_MEK@222' Raf(x~p),MEK(S222~u) -> Raf(x~p!1),MEK(S222~u!1) @ 1.0 # Inactive rule

    11. 

  11. 'eg2' Raf(x~p),MEK(s) -> Raf(x~p!1),MEK(s!1) @ 1.0

    12. 

  12. # 'MEK@222' Raf(x~p!1),MEK(S222~u!1) -> Raf(x~p!1),MEK(S222~p!1) @ 1.0 # Inactive rule

    13. 

  13. # 'Raf_MEK@222_op' Raf(x~p!1),MEK(S222!1) -> Raf(x~p),MEK(S222) @ 1.0 # Inactive rule

    14. 

  14. # 'Raf_MEK@218' Raf(x~p),MEK(S218~u) -> Raf(x~p!1),MEK(S218~u!1) @ 1.0 # Inactive rule

    15. 

  15. # 'MEK@218' Raf(x~p!1),MEK(S218~u!1) -> Raf(x~p!1),MEK(S218~p!1) @ 1.0 # Inactive rule

    16. 

  16. # 'eg1' Raf(x~p!1),MEK(s!1) -> Raf(x~p),MEK(s) @ 1.0 # Inactive rule

    17. 

  17. # 'Raf_MEK@218_op' Raf(x~p!1),MEK(S218!1) -> Raf(x~p),MEK(S218) @ 1.0 # Inactive rule

    18. 

  18. 'PP2A2_MEK@222' PP2A2(s),MEK(S222~p) -> PP2A2(s!1),MEK(S222~p!1) @ 1.0

    19. 

  19. 'MEK@222_op' PP2A2(s!1),MEK(S222~p!1) -> PP2A2(s!1),MEK(S222~u!1) @ 1.0

    20. 

  20. 'PP2A2_MEK@222_op' PP2A2(s!1),MEK(S222!1) -> PP2A2(s),MEK(S222) @ 1.0

    21. 

  21. 'PP2A2_MEK@218' PP2A2(s),MEK(S218~p) -> PP2A2(s!1),MEK(S218~p!1) @ 1.0

    22. 

  22. 'MEK@222_op' PP2A2(s!1),MEK(S218~p!1) -> PP2A2(s!1),MEK(S218~u!1) @ 1.0

    23. 

  23. 'PP2A2_MEK@218_op' PP2A2(s!1),MEK(S218!1) -> PP2A2(s),MEK(S218) @ 1.0

    24. 

  24. 'MEK_ERK@185' MEK(s,S218~p,S222~p),ERK(T185~u) -> MEK(s!1,S218~p,S222~p),ERK(T185~u!1) @ 1.0

    25. 

  25. 'ERK@185' MEK(s!1,S218~p,S222~p),ERK(T185~u!1) -> MEK(s!1,S218~p,S222~p),ERK(T185~p!1) @ 1.0

    26. 

  26. 'MEK_ERK@185_op' MEK(s!1,S218~p,S222~p),ERK(T185!1) -> MEK(s,S218~p,S222~p),ERK(T185) @ 1.0

    27. 

  27. 'MEK_ERK@187' MEK(s,S218~p,S222~p),ERK(Y187~u) -> MEK(s!1,S218~p,S222~p),ERK(Y187~u!1) @ 1.0

    28. 

  28. 'ERK@187' MEK(s!1,S218~p,S222~p),ERK(Y187~u!1) -> MEK(s!1,S218~p,S222~p),ERK(Y187~p!1) @ 1.0

    29. 

  29. 'MEK_ERK@187_op' MEK(s!1,S218~p,S222~p),ERK(Y187!1) -> MEK(s,S218~p,S222~p),ERK(Y187) @ 1.0

    30. 

  30. 'MKP3_ERK@185' MKP3(s),ERK(T185~p) -> MKP3(s!1),ERK(T185~p!1) @ 1.0

    31. 

  31. 'ERK@185_op' MKP3(s!1),ERK(T185~p!1) -> MKP3(s!1),ERK(T185~u!1) @ 1.0

    32. 

  32. 'MKP3_ERK@185_op' MKP3(s!1),ERK(T185!1) -> MKP3(s),ERK(T185) @ 1.0

    33. 

  33. 'MKP3_ERK@187' MKP3(s),ERK(Y187~p) -> MKP3(s!1),ERK(Y187~p!1) @ 1.0

    34. 

  34. 'ERK@187_op' MKP3(s!1),ERK(Y187~p!1) -> MKP3(s!1),ERK(Y187~u!1) @ 1.0

    35. 

  35. 'MKP3_ERK@187_op' MKP3(s!1),ERK(Y187!1) -> MKP3(s),ERK(Y187) @ 1.0

    36. 

  36. 'DeadRules' A(x)->B(x)

    37. 

  37. 

    38. 

  38. # Initial Conditions:

    39. 

  39. %init: 300 * (Ras(S1S2~gtp))

    40. 

  40. %init: 1000 * (Raf(x~u))

    41. 

  41. %init: 200 * (PP2A1(s))

    42. 

  42. %init: 200 * (PP2A2(s))

    43. 

  43. %init: 1000 * (MEK(s,S222~p,S218~p))

    44. 

  44. %init: 1000 * (ERK(s,T185~u,Y187~u))

    45. 

  45. %init: 200 * (MKP3(s))
    46.