/test.data/contact_map/rules/~kappa010.test

http://github.com/kappamodeler/jkappa · Unknown · 384 lines · 384 code · 0 blank · 0 comment · 0 complexity · d48e8729a551a5d407e2150750767f30 MD5 · raw file 

    

  1. 'ATP recycling'A(s~pp),Pi() -> A(s~ppp)
    2. 

  2. 'EGF_ErbB1'EGF(r~ext),ErbB1(L~ext,CR) <-> EGF(r~ext!1),ErbB1(L~ext!1,CR)
    3. 

  3. 'ErbB1_ErbB1'ErbB1(L~ext!_,CR,N,C),ErbB1(L~ext!_,CR,N,C) <-> ErbB1(L~ext!_,CR!1,N,C),ErbB1(L~ext!_,CR!1,N,C)
    4. 

  4. 'ErbB1_ErbB2'ErbB1(L~ext!_,CR,N,C),ErbB2(L~ext,CR,N,C) <-> ErbB1(L~ext!_,CR!1,N,C),ErbB2(L~ext,CR!1,N,C)
    5. 

  5. 'ErbB2_ErbB3'ErbB2(L~ext,CR,N,C),ErbB3(L~ext!_,CR,N,C) <-> ErbB2(L~ext,CR!1,N,C),ErbB3(L~ext!_,CR!1,N,C)
    6. 

  6. 'ErbB2_ErbB4'ErbB2(L~ext,CR,N,C),ErbB4(L~ext!_,CR,N,C) <-> ErbB2(L~ext,CR!1,N,C),ErbB4(L~ext!_,CR!1,N,C)
    7. 

  7. 'ErbB1_ErbB3'ErbB1(L~ext,CR,N,C),ErbB3(L~ext!_,CR,N,C) <-> ErbB1(L~ext,CR!1,N,C),ErbB3(L~ext!_,CR!1,N,C)
    8. 

  8. 'ErbB1_ErbB4'ErbB1(L~ext,CR,N,C),ErbB4(L~ext!_,CR,N,C) <-> ErbB1(L~ext,CR!1,N,C),ErbB4(L~ext!_,CR!1,N,C)
    9. 

  9. 'ErbB1_ATP'ErbB1(bp),A(s~ppp) -> ErbB1(bp!1),A(s~ppp!1)
    10. 

  10. 'ErbB1_A_op'ErbB1(bp!1),A(s!1) -> ErbB1(bp),A(s)
    11. 

  11. 'ErbB2_ATP'ErbB2(bp),A(s~ppp) -> ErbB2(bp!1),A(s~ppp!1)
    12. 

  12. 'ErbB2_A_op'ErbB2(bp!1),A(s!1) -> ErbB2(bp),A(s)
    13. 

  13. 'ErbB4_ATP'ErbB4(bp),A(s~ppp) -> ErbB4(bp!1),A(s~ppp!1)
    14. 

  14. 'ErbB4_A_op'ErbB4(bp!1),A(s!1) -> ErbB4(bp),A(s)
    15. 

  15. 'Rule1'ErbB1(CR!1,N,C),ErbB1(CR!1,N,C) <-> ErbB1(CR!1,N!2,C),ErbB1(CR!1,N,C!2)
    16. 

  16. 'Rule2'ErbB2(CR!1,N,C),ErbB1(CR!1,N,C) <-> ErbB2(CR!1,N!2,C),ErbB1(CR!1,N,C!2)
    17. 

  17. 'Rule3'ErbB4(CR!1,N,C),ErbB1(CR!1,N,C) <-> ErbB4(CR!1,N!2,C),ErbB1(CR!1,N,C!2)
    18. 

  18. 'Rule4'ErbB1(N!1,bp!2),ErbB1(C!1,Y992~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB1(C!1,Y992~p),A(s~pp!2)
    19. 

  19. 'Rule5'ErbB1(N!1,bp!2),ErbB1(C!1,Y1068~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB1(C!1,Y1068~p),A(s~pp!2)
    20. 

  20. 'Rule6'ErbB1(N!1,bp!2),ErbB1(C!1,Y1148~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB1(C!1,Y1148~p),A(s~pp!2)
    21. 

  21. 'Rule7'ErbB2(N!1,bp!2),ErbB1(C!1,Y992~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB1(C!1,Y992~p),A(s~pp!2)
    22. 

  22. 'Rule8'ErbB2(N!1,bp!2),ErbB1(C!1,Y1068~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB1(C!1,Y1068~p),A(s~pp!2)
    23. 

  23. 'Rule9'ErbB4(N!1,bp!2),ErbB1(C!1,Y992~u),A(s~ppp!2) -> ErbB4(N!1,bp!2),ErbB1(C!1,Y992~p),A(s~pp!2)
    24. 

  24. 'Rule10'ErbB4(N!1,bp!2),ErbB1(C!1,Y1068~u),A(s~ppp!2) -> ErbB4(N!1,bp!2),ErbB1(C!1,Y1068~p),A(s~pp!2)
    25. 

  25. 'Rule11'ErbB4(N!1,bp!2),ErbB1(C!1,Y1148~u),A(s~ppp!2) -> ErbB4(N!1,bp!2),ErbB1(C!1,Y1148~p),A(s~pp!2)
    26. 

  26. 'Rule12'ErbB1(CR!1,N,C),ErbB2(CR!1,N,C) <-> ErbB1(CR!1,N!2,C),ErbB2(CR!1,N,C!2)
    27. 

  27. 'Rule13'ErbB2(CR!1,N,C),ErbB2(CR!1,N,C) <-> ErbB2(CR!1,N!2,C),ErbB2(CR!1,N,C!2)
    28. 

  28. 'Rule14'ErbB4(CR!1,N,C),ErbB2(CR!1,N,C) <-> ErbB4(CR!1,N!2,C),ErbB2(CR!1,N,C!2)
    29. 

  29. 'Rule15'ErbB1(N!1,bp!2),ErbB2(C!1,Y1139~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB2(C!1,Y1139~p),A(s~pp!2)
    30. 

  30. 'Rule16'ErbB1(N!1,bp!2),ErbB2(C!1,Y1196~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB2(C!1,Y1196~p),A(s~pp!2)
    31. 

  31. 'Rule17'ErbB1(N!1,bp!2),ErbB2(C!1,Y1221~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB2(C!1,Y1221~p),A(s~pp!2)
    32. 

  32. 'Rule18'ErbB4(N!1,bp!2),ErbB2(C!1,Y1139~u),A(s~ppp!2) -> ErbB4(N!1,bp!2),ErbB2(C!1,Y1139~p),A(s~pp!2)
    33. 

  33. 'Rule19'ErbB4(N!1,bp!2),ErbB2(C!1,Y1196~u),A(s~ppp!2) -> ErbB4(N!1,bp!2),ErbB2(C!1,Y1196~p),A(s~pp!2)
    34. 

  34. 'Rule20'ErbB4(N!1,bp!2),ErbB2(C!1,Y1221~u),A(s~ppp!2) -> ErbB4(N!1,bp!2),ErbB2(C!1,Y1221~p),A(s~pp!2)
    35. 

  35. 'Rule21'ErbB1(CR!1,N,C),ErbB3(CR!1,C,N) <-> ErbB1(CR!1,N!2,C),ErbB3(CR!1,C!2,N)
    36. 

  36. 'Rule22'ErbB2(CR!1,N,C),ErbB3(CR!1,C,N) <-> ErbB2(CR!1,N!2,C),ErbB3(CR!1,C!2,N)
    37. 

  37. 'Rule23'ErbB1(N!1,bp!2),ErbB3(C!1,Y1035~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB3(C!1,Y1035~p),A(s~pp!2)
    38. 

  38. 'Rule24'ErbB1(N!1,bp!2),ErbB3(C!1,Y1178~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB3(C!1,Y1178~p),A(s~pp!2)
    39. 

  39. 'Rule25'ErbB1(N!1,bp!2),ErbB3(C!1,Y1203~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB3(C!1,Y1203~p),A(s~pp!2)
    40. 

  40. 'Rule26'ErbB1(N!1,bp!2),ErbB3(C!1,Y1241~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB3(C!1,Y1241~p),A(s~pp!2)
    41. 

  41. 'Rule27'ErbB1(N!1,bp!2),ErbB3(C!1,Y1257~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB3(C!1,Y1257~p),A(s~pp!2)
    42. 

  42. 'Rule28'ErbB1(N!1,bp!2),ErbB3(C!1,Y1270~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB3(C!1,Y1270~p),A(s~pp!2)
    43. 

  43. 'Rule29'ErbB1(N!1,bp!2),ErbB3(C!1,Y1309~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB3(C!1,Y1309~p),A(s~pp!2)
    44. 

  44. 'Rule30'ErbB2(N!1,bp!2),ErbB3(C!1,Y1035~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB3(C!1,Y1035~p),A(s~pp!2)
    45. 

  45. 'Rule31'ErbB2(N!1,bp!2),ErbB3(C!1,Y1178~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB3(C!1,Y1178~p),A(s~pp!2)
    46. 

  46. 'Rule32'ErbB2(N!1,bp!2),ErbB3(C!1,Y1203~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB3(C!1,Y1203~p),A(s~pp!2)
    47. 

  47. 'Rule33'ErbB2(N!1,bp!2),ErbB3(C!1,Y1241~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB3(C!1,Y1241~p),A(s~pp!2)
    48. 

  48. 'Rule34'ErbB2(N!1,bp!2),ErbB3(C!1,Y1257~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB3(C!1,Y1257~p),A(s~pp!2)
    49. 

  49. 'Rule35'ErbB2(N!1,bp!2),ErbB3(C!1,Y1270~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB3(C!1,Y1270~p),A(s~pp!2)
    50. 

  50. 'Rule36'ErbB2(N!1,bp!2),ErbB3(C!1,Y1309~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB3(C!1,Y1309~p),A(s~pp!2)
    51. 

  51. 'Rule37'ErbB1(CR!1,N,C),ErbB4(CR!1,N,C) <-> ErbB1(CR!1,N!2,C),ErbB4(CR!1,N,C!2)
    52. 

  52. 'Rule38'ErbB2(CR!1,N,C),ErbB4(CR!1,N,C) <-> ErbB2(CR!1,N!2,C),ErbB4(CR!1,N,C!2)
    53. 

  53. 'Rule39'ErbB1(N!1,bp!2),ErbB4(C!1,Y1056~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB4(C!1,Y1056~p),A(s~pp!2)
    54. 

  54. 'Rule40'ErbB1(N!1,bp!2),ErbB4(C!1,Y1188~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB4(C!1,Y1188~p),A(s~pp!2)
    55. 

  55. 'Rule41'ErbB1(N!1,bp!2),ErbB4(C!1,Y1242~u),A(s~ppp!2) -> ErbB1(N!1,bp!2),ErbB4(C!1,Y1242~p),A(s~pp!2)
    56. 

  56. 'Rule42'ErbB2(N!1,bp!2),ErbB4(C!1,Y1056~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB4(C!1,Y1056~p),A(s~pp!2)
    57. 

  57. 'Rule43'ErbB2(N!1,bp!2),ErbB4(C!1,Y1188~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB4(C!1,Y1188~p),A(s~pp!2)
    58. 

  58. 'Rule44'ErbB2(N!1,bp!2),ErbB4(C!1,Y1242~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB4(C!1,Y1242~p),A(s~pp!2)
    59. 

  59. 'Rule45'ErbB1(Y992~p) -> ErbB1(Y992~u),Pi()
    60. 

  60. 'Rule46'ErbB1(Y1068~p) -> ErbB1(Y1068~u),Pi()
    61. 

  61. 'Rule47'ErbB1(Y1148~p) -> ErbB1(Y1148~u),Pi()
    62. 

  62. 'Rule48'ErbB2(Y1139~p) -> ErbB2(Y1139~u),Pi()
    63. 

  63. 'Rule49'ErbB2(Y1196~p) -> ErbB2(Y1196~u),Pi()
    64. 

  64. 'Rule50'ErbB2(Y1221~p) -> ErbB2(Y1221~u),Pi()
    65. 

  65. 'ErbB1_RasGAP'ErbB1(Y992~p),RasGAP(SH2) <-> ErbB1(Y992~p!1),RasGAP(SH2!1)
    66. 

  66. 'ErbB2_RasGAP'ErbB2(Y1221~p),RasGAP(SH2) <-> ErbB2(Y1221~p!1),RasGAP(SH2!1)
    67. 

  67. 'ErbB1_Grb2'ErbB1(Y1068~p),Grb2(SH2) <-> ErbB1(Y1068~p!1),Grb2(SH2!1)
    68. 

  68. 'ErbB2_Grb2'ErbB2(Y1139~p),Grb2(SH2) <-> ErbB2(Y1139~p!1),Grb2(SH2!1)
    69. 

  69. 'ErbB1_Shc'ErbB1(Y1148~p),Shc(PTB) <-> ErbB1(Y1148~p!1),Shc(PTB!1)
    70. 

  70. 'ErbB2_Shc#1'ErbB2(Y1196~p),Shc(PTB) <-> ErbB2(Y1196~p!1),Shc(PTB!1)
    71. 

  71. 'ErbB2_Shc#2'ErbB2(Y1221~p),Shc(PTB) <-> ErbB2(Y1221~p!1),Shc(PTB!1)
    72. 

  72. 'Shc#1'ErbB1(Y1148~p!1),Shc(PTB!1,Y318~u) -> ErbB1(Y1148~p!1),Shc(PTB!1,Y318~p)
    73. 

  73. 'Shc#2'ErbB2(Y1196~p!1),Shc(PTB!1,Y318~u) -> ErbB2(Y1196~p!1),Shc(PTB!1,Y318~p)
    74. 

  74. 'Shc#3'ErbB2(Y1221~p!1),Shc(PTB!1,Y318~u) -> ErbB2(Y1221~p!1),Shc(PTB!1,Y318~p)
    75. 

  75. 'long arm SoS_Ras#1'ErbB1(Y1148~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b),Ras(S1S2~gdp) -> ErbB1(Y1148~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b!4),Ras(S1S2~gdp!4)
    76. 

  76. 'long arm SoS_Ras#2'ErbB2(Y1196~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b),Ras(S1S2~gdp) -> ErbB2(Y1196~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b!4),Ras(S1S2~gdp!4)
    77. 

  77. 'long arm SoS_Ras#3'ErbB2(Y1221~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b),Ras(S1S2~gdp) -> ErbB2(Y1221~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b!4),Ras(S1S2~gdp!4)
    78. 

  78. 'short arm SoS_Ras#1'ErbB1(Y1068~p!1),Grb2(SH2!1,SH3n!2),SoS(a!2,b),Ras(S1S2~gdp) -> ErbB1(Y1068~p!1),Grb2(SH2!1,SH3n!2),SoS(a!2,b!3),Ras(S1S2~gdp!3)
    79. 

  79. 'short arm SoS_Ras#2'ErbB2(Y1139~p!1),Grb2(SH2!1,SH3n!2),SoS(a!2,b),Ras(S1S2~gdp) -> ErbB2(Y1139~p!1),Grb2(SH2!1,SH3n!2),SoS(a!2,b!3),Ras(S1S2~gdp!3)
    80. 

  80. 'direct RasGAP_Ras#1'ErbB1(Y992~p!1),RasGAP(SH2!1,s),Ras(S1S2~gtp) -> ErbB1(Y992~p!1),RasGAP(SH2!1,s!2),Ras(S1S2~gtp!2)
    81. 

  81. 'direct RasGAP_Ras#2'ErbB2(Y1221~p!1),RasGAP(SH2!1,s),Ras(S1S2~gtp) -> ErbB2(Y1221~p!1),RasGAP(SH2!1,s!2),Ras(S1S2~gtp!2)
    82. 

  82. 'Gab1@447#1'ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~u) -> ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~p)
    83. 

  83. 'Gab1@472#1'ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~u) -> ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~p)
    84. 

  84. 'Gab1@619#1'ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~u) -> ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~p)
    85. 

  85. 'Gab1@447#2'ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~u) -> ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~p)
    86. 

  86. 'Gab1@472#2'ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~u) -> ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~p)
    87. 

  87. 'Gab1@619#2'ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~u) -> ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~p)
    88. 

  88. 'short arm PI3K_PI#1'ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~p!3),PI3K(SH2!3,s),PI(three~u) -> ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~p!3),PI3K(SH2!3,s!4),PI(three~u!4)
    89. 

  89. 'short arm PI3K_PI#2'ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~p!3),PI3K(SH2!3,s),PI(three~u) -> ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~p!3),PI3K(SH2!3,s!4),PI(three~u!4)
    90. 

  90. 'short arm PI3K_PI#3'ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~p!3),PI3K(SH2!3,s),PI(three~u) -> ErbB1(Y1068~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~p!3),PI3K(SH2!3,s!4),PI(three~u!4)
    91. 

  91. 'short arm PI3K_PI#4'ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~p!3),PI3K(SH2!3,s),PI(three~u) -> ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y447~p!3),PI3K(SH2!3,s!4),PI(three~u!4)
    92. 

  92. 'short arm PI3K_PI#5'ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~p!3),PI3K(SH2!3,s),PI(three~u) -> ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y472~p!3),PI3K(SH2!3,s!4),PI(three~u!4)
    93. 

  93. 'short arm PI3K_PI#6'ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~p!3),PI3K(SH2!3,s),PI(three~u) -> ErbB2(Y1139~p!1),Grb2(SH2!1,SH3c!2),Gab1(PR!2,Y619~p!3),PI3K(SH2!3,s!4),PI(three~u!4)
    94. 

  94. 'EGFR_p@Y1086'EGFR(N!1,bp!2),EGFR(C!1,Y1086~u),A(s~ppp!2) -> EGFR(N!1,bp!2),EGFR(C!1,Y1086~p),A(s~pp!2)
    95. 

  95. 'EGFR_p@Y1173'EGFR(N!1,bp!2),EGFR(C!1,Y1173~u),A(s~ppp!2) -> EGFR(N!1,bp!2),EGFR(C!1,Y1173~p),A(s~pp!2)
    96. 

  96. 'New Rule'A(x~u) <-> A(x~p)
    97. 

  97. 'Rule51'A(x~p),B(x1) -> A(x~p!1),B(x1!1)
    98. 

  98. 'Rule52'A(x!1),B(x1!1) -> A(x),B(x1)
    99. 

  99. 'Rule53'A(x!1),B(x1!1,y1~u) -> A(x!1),B(x1!1,y1~p)
    100. 

  100. 'Rule54'A(x~p),B(x2) -> A(x~p!1),B(x2!1)
    101. 

  101. 'Rule55'A(x!1),B(x2!1) -> A(x),B(x2)
    102. 

  102. 'Rule56'A(x!1),B(x2!1,y2~u) -> A(x!1),B(x2!1,y2~p)
    103. 

  103. 'HRG_ErbB3'HRG(r~ext),ErbB3(L~ext,CR) <-> HRG(r~ext!1),ErbB3(L~ext!1,CR)
    104. 

  104. 'HRG_ErbB4'HRG(r~ext),ErbB4(L~ext,CR) <-> HRG(r~ext!1),ErbB4(L~ext!1,CR)
    105. 

  105. 'Rule57'ErbB3(Y1035~p) -> ErbB3(Y1035~u),Pi()
    106. 

  106. 'Rule58'ErbB3(Y1178~p) -> ErbB3(Y1178~u),Pi()
    107. 

  107. 'Rule59'ErbB3(Y1203~p) -> ErbB3(Y1203~u),Pi()
    108. 

  108. 'Rule60'ErbB3(Y1241~p) -> ErbB3(Y1241~u),Pi()
    109. 

  109. 'Rule61'ErbB3(Y1257~p) -> ErbB3(Y1257~u),Pi()
    110. 

  110. 'Rule62'ErbB3(Y1270~p) -> ErbB3(Y1270~u),Pi()
    111. 

  111. 'Rule63'ErbB3(Y1309~p) -> ErbB3(Y1309~u),Pi()
    112. 

  112. 'Rule64'ErbB4(Y1056~p) -> ErbB4(Y1056~u),Pi()
    113. 

  113. 'Rule65'ErbB4(Y1188~p) -> ErbB4(Y1188~u),Pi()
    114. 

  114. 'Rule66'ErbB4(Y1242~p) -> ErbB4(Y1242~u),Pi()
    115. 

  115. 'ErbB3_Shc'ErbB3(Y1309~p),Shc(PTB) <-> ErbB3(Y1309~p!1),Shc(PTB!1)
    116. 

  116. 'Shc#4'ErbB3(Y1309~p!1),Shc(PTB!1,Y318~u) -> ErbB3(Y1309~p!1),Shc(PTB!1,Y318~p)
    117. 

  117. 'Shc_op'Shc(Y318~p) -> Shc(Y318~u),Pi()
    118. 

  118. 'Shc_Grb2'Shc(Y318~p),Grb2(SH2) <-> Shc(Y318~p!1),Grb2(SH2!1)
    119. 

  119. 'Grb2_SoS'Grb2(SH3),SoS(a,SS~u) -> Grb2(SH3!1),SoS(a!1,SS~u)
    120. 

  120. 'Grb2_SoS_op'Grb2(SH3!1),SoS(a!1) -> Grb2(SH3),SoS(a)
    121. 

  121. 'long arm SoS_Ras#4'ErbB3(Y1309~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b),Ras(S1S2~gdp) -> ErbB3(Y1309~p!1),Shc(PTB!1,Y318~p!2),Grb2(SH2!2,SH3n!3),SoS(a!3,b!4),Ras(S1S2~gdp!4)
    122. 

  122. 'Ras GTP'SoS(b!1),Ras(S1S2~gdp!1) -> SoS(b!1),Ras(S1S2~gtp!1)
    123. 

  123. 'SoS_Ras_op'SoS(b!1),Ras(S1S2!1) -> SoS(b),Ras(S1S2)
    124. 

  124. 'Ras GDP'RasGAP(s!1),Ras(S1S2~gtp!1) -> RasGAP(s!1),Ras(S1S2~gdp!1)
    125. 

  125. 'RasGAP_Ras_op'RasGAP(s!1),Ras(S1S2!1) -> RasGAP(s),Ras(S1S2)
    126. 

  126. 'Grb2_Gab1'Grb2(SH3c),Gab1(PR) <-> Grb2(SH3c!1),Gab1(PR!1)
    127. 

  127. 'Gab1_PI3K@447'Gab1(Y447~p),PI3K(SH2) <-> Gab1(Y447~p!1),PI3K(SH2!1)
    128. 

  128. 'Gab1_PI3K@472'Gab1(Y472~p),PI3K(SH2) <-> Gab1(Y472~p!1),PI3K(SH2!1)
    129. 

  129. 'Gab1_PI3K@619'Gab1(Y619~p),PI3K(SH2) <-> Gab1(Y619~p!1),PI3K(SH2!1)
    130. 

  130. 'Gab1_Shp2@447'Gab1(Y447~p),Shp2(s) -> Gab1(Y447~p!1),Shp2(s!1)
    131. 

  131. 'Gab1_Shp2@472'Gab1(Y472~p),Shp2(s) -> Gab1(Y472~p!1),Shp2(s!1)
    132. 

  132. 'Gab1_Shp2@619'Gab1(Y619~p),Shp2(s) -> Gab1(Y619~p!1),Shp2(s!1)
    133. 

  133. 'Gab1@447_op'Gab1(Y447~p!1),Shp2(s!1) -> Gab1(Y447~u!1),Shp2(s!1),Pi()
    134. 

  134. 'Gab1@472_op'Gab1(Y472~p!1),Shp2(s!1) -> Gab1(Y472~u!1),Shp2(s!1),Pi()
    135. 

  135. 'Gab1@619_op'Gab1(Y619~p!1),Shp2(s!1) -> Gab1(Y619~u!1),Shp2(s!1),Pi()
    136. 

  136. 'Gab1_Shp2@447_op'Gab1(Y447!1),Shp2(s!1) -> Gab1(Y447),Shp2(s)
    137. 

  137. 'Gab1_Shp2@472_op'Gab1(Y472!1),Shp2(s!1) -> Gab1(Y472),Shp2(s)
    138. 

  138. 'Gab1_Shp2@619_op'Gab1(Y619!1),Shp2(s!1) -> Gab1(Y619),Shp2(s)
    139. 

  139. 'ErbB3_PI3K#1'ErbB3(Y1035~p),PI3K(SH2) <-> ErbB3(Y1035~p!1),PI3K(SH2!1)
    140. 

  140. 'ErbB3_PI3K#2'ErbB3(Y1178~p),PI3K(SH2) <-> ErbB3(Y1178~p!1),PI3K(SH2!1)
    141. 

  141. 'ErbB3_PI3K#3'ErbB3(Y1203~p),PI3K(SH2) <-> ErbB3(Y1203~p!1),PI3K(SH2!1)
    142. 

  142. 'ErbB3_PI3K#4'ErbB3(Y1241~p),PI3K(SH2) <-> ErbB3(Y1241~p!1),PI3K(SH2!1)
    143. 

  143. 'ErbB3_PI3K#5'ErbB3(Y1257~p),PI3K(SH2) <-> ErbB3(Y1257~p!1),PI3K(SH2!1)
    144. 

  144. 'ErbB3_PI3K#6'ErbB3(Y1270~p),PI3K(SH2) <-> ErbB3(Y1270~p!1),PI3K(SH2!1)
    145. 

  145. 'direct PI3K_PI#1'ErbB3(Y1035~p!1),PI3K(SH2!1,s),PI(three~u) -> ErbB3(Y1035~p!1),PI3K(SH2!1,s!2),PI(three~u!2)
    146. 

  146. 'direct PI3K_PI#2'ErbB3(Y1178~p!1),PI3K(SH2!1,s),PI(three~u) -> ErbB3(Y1178~p!1),PI3K(SH2!1,s!2),PI(three~u!2)
    147. 

  147. 'direct PI3K_PI#3'ErbB3(Y1203~p!1),PI3K(SH2!1,s),PI(three~u) -> ErbB3(Y1203~p!1),PI3K(SH2!1,s!2),PI(three~u!2)
    148. 

  148. 'direct PI3K_PI#4'ErbB3(Y1241~p!1),PI3K(SH2!1,s),PI(three~u) -> ErbB3(Y1241~p!1),PI3K(SH2!1,s!2),PI(three~u!2)
    149. 

  149. 'direct PI3K_PI#5'ErbB3(Y1257~p!1),PI3K(SH2!1,s),PI(three~u) -> ErbB3(Y1257~p!1),PI3K(SH2!1,s!2),PI(three~u!2)
    150. 

  150. 'direct PI3K_PI#6'ErbB3(Y1270~p!1),PI3K(SH2!1,s),PI(three~u) -> ErbB3(Y1270~p!1),PI3K(SH2!1,s!2),PI(three~u!2)
    151. 

  151. 'PI@three'PI3K(s!1),PI(three~u!1) -> PI3K(s!1),PI(three~p!1)
    152. 

  152. 'PI3K_PI_op'PI3K(s!1),PI(three!1) -> PI3K(s),PI(three)
    153. 

  153. 'PTEN_PI'PTEN(s),PI(three~p) -> PTEN(s!1),PI(three~p!1)
    154. 

  154. 'PI@three_op'PTEN(s!1),PI(three~p!1) -> PTEN(s!1),PI(three~u!1)
    155. 

  155. 'PTEN_PI_op'PTEN(s!1),PI(three!1) -> PTEN(s),PI(three)
    156. 

  156. 'PIP3_PDK1'PI(three~p,four~p,five~p),PDK1(PH) -> PI(three~p!1,four~p,five~p),PDK1(PH!1)
    157. 

  157. 'PIP3_PDK1_op'PI(three!1),PDK1(PH!1) -> PI(three),PDK1(PH)
    158. 

  158. 'PIP3_Akt'PI(three~p,four~p,five~p),Akt(PH) -> PI(three~p!1,four~p,five~p),Akt(PH!1)
    159. 

  159. 'PIP3_Akt_op'PI(three!1),Akt(PH!1) -> PI(three),Akt(PH)
    160. 

  160. 'Ras_Raf'Ras(S1S2~gtp),Raf(x~u) -> Ras(S1S2~gtp!1),Raf(x~u!1)
    161. 

  161. 'Raf'Ras(S1S2~gtp!1),Raf(x~u!1) -> Ras(S1S2~gtp!1),Raf(x~p!1)
    162. 

  162. 'Ras_Raf_op'Ras(S1S2~gtp!1),Raf(x!1) -> Ras(S1S2~gtp),Raf(x)
    163. 

  163. 'SoS_ERK'SoS(SS),ERK(s,T185~p,Y187~p) <-> SoS(SS!1),ERK(s!1,T185~p,Y187~p)
    164. 

  164. 'SoS@SS'SoS(SS~u!1),ERK(s!1,T185~p,Y187~p) -> SoS(SS~p!1),ERK(s!1,T185~p,Y187~p)
    165. 

  165. 'SoS@SS_op'SoS(SS~p) -> SoS(SS~u),Pi()
    166. 

  166. 'Rule67'E() -> EGF(r~ext)
    167. 

  167. 'EGF_EGFRe'EGF(r~ext),EGFR(L~ext,CR) -> EGF(r~ext!1),EGFR(L~ext!1,CR)
    168. 

  168. 'EGF_EGFRi'EGF(r~int),EGFR(L~int,CR) -> EGF(r~int!1),EGFR(L~int!1,CR)
    169. 

  169. 'EGF_EGFR_op'EGF(r!1),EGFR(L!1) -> EGF(r),EGFR(L)
    170. 

  170. 'EGFR_EGFRe'EGFR(L~ext!_,CR,N,C),EGFR(L~ext!_,CR,N,C) -> EGFR(L~ext!_,CR!1,N,C),EGFR(L~ext!_,CR!1,N,C)
    171. 

  171. 'EGFR_EGFRi'EGFR(L~int!_,CR,N,C),EGFR(L~int!_,CR,N,C) -> EGFR(L~int!_,CR!1,N,C),EGFR(L~int!_,CR!1,N,C)
    172. 

  172. 'EGFR_HER2'EGFR(L~ext!_,CR,N,C),HER2(CR,N,C) -> EGFR(L~ext!_,CR!1,N,C),HER2(CR!1,N,C)
    173. 

  173. 'EGFR_HER3'EGFR(L~ext!_,CR,N,C),HER3(L~ext!_,CR,C) -> EGFR(L~ext!_,CR!1,N,C),HER3(L~ext!_,CR!1,C)
    174. 

  174. 'EGFR_HER4'EGFR(L~ext!_,CR,N,C),HER4(L~ext!_,CR,N,C) -> EGFR(L~ext!_,CR!1,N,C),HER4(L~ext!_,CR!1,N,C)
    175. 

  175. 'EGFR_EGFR_op'EGFR(CR!1,N,C),EGFR(CR!1,N,C) -> EGFR(CR,N,C),EGFR(CR,N,C)
    176. 

  176. 'EGFR_HER2_op'EGFR(CR!1,N,C),HER2(CR!1,N,C) -> EGFR(CR,N,C),HER2(CR,N,C)
    177. 

  177. 'EGFR_HER3_op'EGFR(CR!1,N,C),HER3(CR!1,C) -> EGFR(CR,N,C),HER3(CR,C)
    178. 

  178. 'EGFR_HER4_op'EGFR(CR!1,N,C),HER4(CR!1,N,C) -> EGFR(CR,N,C),HER4(CR,N,C)
    179. 

  179. '11 dimer'EGFR(CR!1,N,C),EGFR(CR!1,N,C) <-> EGFR(CR!1,N!2,C),EGFR(CR!1,N,C!2)
    180. 

  180. '21 dimer'HER2(CR!1,N,C),EGFR(CR!1,N,C) <-> HER2(CR!1,N!2,C),EGFR(CR!1,N,C!2)
    181. 

  181. '41 dimer'HER4(CR!1,N,C),EGFR(CR!1,N,C) <-> HER4(CR!1,N!2,C),EGFR(CR!1,N,C!2)
    182. 

  182. '12 dimer'EGFR(CR!1,N,C),HER2(CR!1,N,C) <-> EGFR(CR!1,N!2,C),HER2(CR!1,N,C!2)
    183. 

  183. '13 dimer'EGFR(CR!1,N,C),HER3(CR!1,C) <-> EGFR(CR!1,N!2,C),HER3(CR!1,C!2)
    184. 

  184. '14 dimer'EGFR(CR!1,N,C),HER4(CR!1,N,C) <-> EGFR(CR!1,N!2,C),HER4(CR!1,N,C!2)
    185. 

  185. 'EGFR_Inh'EGFR(N!_,bp),Inh1(s) -> EGFR(N!_,bp!1),Inh1(s!1)
    186. 

  186. 'EGFR_Inh_op'EGFR(bp!1),Inh1(s!1) -> EGFR(bp),Inh1(s)
    187. 

  187. 'EGF_mono'EGF(r~ext!1),EGFR(L~ext!1,CR) -> EGF(r~int!1),EGFR(L~int!1,CR)
    188. 

  188. 'EGF_di'EGF(r~ext!1),EGFR(L~ext!1,CR!2),EGF(r~ext!3),EGFR(L~ext!3,CR!2) -> EGF(r~int!1),EGFR(L~int!1,CR!2),EGF(r~int!3),EGFR(L~int!3,CR!2)
    189. 

  189. 'Rule68'EGFR(N!1,bp),EGFR(C!1,Y1016~u) -> EGFR(N!1,bp),EGFR(C!1,Y1016~p)
    190. 

  190. 'Rule69'HER2(N!1,bp),EGFR(C!1,Y1016~u) -> HER2(N!1,bp),EGFR(C!1,Y1016~p)
    191. 

  191. 'Rule70'HER4(N!1,bp),EGFR(C!1,Y1016~u) -> HER4(N!1,bp),EGFR(C!1,Y1016~p)
    192. 

  192. 'Rule71'EGFR(N!1,bp),EGFR(C!1,Y1092~u) -> EGFR(N!1,bp),EGFR(C!1,Y1092~p)
    193. 

  193. 'Rule72'HER2(N!1,bp),EGFR(C!1,Y1092~u) -> HER2(N!1,bp),EGFR(C!1,Y1092~p)
    194. 

  194. 'Rule73'HER4(N!1,bp),EGFR(C!1,Y1092~u) -> HER4(N!1,bp),EGFR(C!1,Y1092~p)
    195. 

  195. 'Rule74'EGFR(N!1,bp),EGFR(C!1,Y1172~u) -> EGFR(N!1,bp),EGFR(C!1,Y1172~p)
    196. 

  196. 'Rule75'HER2(N!1,bp),EGFR(C!1,Y1172~u) -> HER2(N!1,bp),EGFR(C!1,Y1172~p)
    197. 

  197. 'Rule76'HER4(N!1,bp),EGFR(C!1,Y1172~u) -> HER4(N!1,bp),EGFR(C!1,Y1172~p)
    198. 

  198. 'Rule77'EGFR(N!1,bp),HER2(C!1,Y1139~u) -> EGFR(N!1,bp),HER2(C!1,Y1139~p)
    199. 

  199. 'Rule78'EGFR(N!1,bp),HER2(C!1,Y1196~u) -> EGFR(N!1,bp),HER2(C!1,Y1196~p)
    200. 

  200. 'Rule79'EGFR(N!1,bp),HER2(C!1,Y1221~u) -> EGFR(N!1,bp),HER2(C!1,Y1221~p)
    201. 

  201. 'Rule80'EGFR(N!1,bp),HER3(C!1,Y1035~u) -> EGFR(N!1,bp),HER3(C!1,Y1035~p)
    202. 

  202. 'Rule81'EGFR(N!1,bp),HER3(C!1,Y1178~u) -> EGFR(N!1,bp),HER3(C!1,Y1178~p)
    203. 

  203. 'Rule82'EGFR(N!1,bp),HER3(C!1,Y1203~u) -> EGFR(N!1,bp),HER3(C!1,Y1203~p)
    204. 

  204. 'Rule83'EGFR(N!1,bp),HER3(C!1,Y1241~u) -> EGFR(N!1,bp),HER3(C!1,Y1241~p)
    205. 

  205. 'Rule84'EGFR(N!1,bp),HER3(C!1,Y1257~u) -> EGFR(N!1,bp),HER3(C!1,Y1257~p)
    206. 

  206. 'Rule85'EGFR(N!1,bp),HER3(C!1,Y1270~u) -> EGFR(N!1,bp),HER3(C!1,Y1270~p)
    207. 

  207. 'Rule86'EGFR(N!1,bp),HER3(C!1,Y1309~u) -> EGFR(N!1,bp),HER3(C!1,Y1309~p)
    208. 

  208. 'Rule87'EGFR(N!1,bp),HER4(C!1,Y1~u) -> EGFR(N!1,bp),HER4(C!1,Y1~p)
    209. 

  209. 'Rule88'EGFR(N!1,bp),HER4(C!1,Y2~u) -> EGFR(N!1,bp),HER4(C!1,Y2~p)
    210. 

  210. 'Rule89'EGFR(N!1,bp),HER4(C!1,Y3~u) -> EGFR(N!1,bp),HER4(C!1,Y3~p)
    211. 

  211. 'Rule90'EGFR(Y1016~p),PTP(s) -> EGFR(Y1016~p!1),PTP(s!1)
    212. 

  212. 'Rule91'EGFR(Y1092~p),PTP(s) -> EGFR(Y1092~p!1),PTP(s!1)
    213. 

  213. 'Rule92'EGFR(Y1172~p),PTP(s) -> EGFR(Y1172~p!1),PTP(s!1)
    214. 

  214. 'Rule93'EGFR(Y1016!1),PTP(s!1) -> EGFR(Y1016),PTP(s)
    215. 

  215. 'Rule94'EGFR(Y1092!1),PTP(s!1) -> EGFR(Y1092),PTP(s)
    216. 

  216. 'Rule95'EGFR(Y1172!1),PTP(s!1) -> EGFR(Y1172),PTP(s)
    217. 

  217. 'Rule96'EGFR(Y1016~p!1),PTP(s!1) -> EGFR(Y1016~u!1),PTP(s!1)
    218. 

  218. 'Rule97'EGFR(Y1092~p!1),PTP(s!1) -> EGFR(Y1092~u!1),PTP(s!1)
    219. 

  219. 'Rule98'EGFR(Y1172~p!1),PTP(s!1) -> EGFR(Y1172~u!1),PTP(s!1)
    220. 

  220. 'deg_EGF'EGF(r~int) ->
    221. 

  221. 'deg_EGFR'EGFR(L~int,CR) ->
    222. 

  222. 'EGFR_RasGAP'EGFR(Y1016~p),RasGAP(SH2~u) <-> EGFR(Y1016~p!1),RasGAP(SH2~rec!1)
    223. 

  223. 'EGFR_Grb2'EGFR(Y1092~p),Grb2(SH2~u) <-> EGFR(Y1092~p!1),Grb2(SH2~rec!1)
    224. 

  224. 'EGFR_Shc'EGFR(Y1172~p),Shc(PTB~u) <-> EGFR(Y1172~p!1),Shc(PTB~rec!1)
    225. 

  225. 'HER2_Grb2'HER2(Y1139~p),Grb2(SH2~u) <-> HER2(Y1139~p!1),Grb2(SH2~rec!1)
    226. 

  226. 'HER2_Shc#1'HER2(Y1196~p),Shc(PTB~u) <-> HER2(Y1196~p!1),Shc(PTB~rec!1)
    227. 

  227. 'HER2_RasGAP'HER2(Y1221~p),RasGAP(SH2~u) <-> HER2(Y1221~p!1),RasGAP(SH2~rec!1)
    228. 

  228. 'HER2_Shc#2'HER2(Y1221~p),Shc(PTB~u) <-> HER2(Y1221~p!1),Shc(PTB~rec!1)
    229. 

  229. 'HER3_PI3K#1'HER3(Y1035~p),PI3K(SH2~u) <-> HER3(Y1035~p!1),PI3K(SH2~rec!1)
    230. 

  230. 'HER3_PI3K#2'HER3(Y1178~p),PI3K(SH2~u) <-> HER3(Y1178~p!1),PI3K(SH2~rec!1)
    231. 

  231. 'HER3_PI3K#3'HER3(Y1203~p),PI3K(SH2~u) <-> HER3(Y1203~p!1),PI3K(SH2~rec!1)
    232. 

  232. 'HER3_PI3K#4'HER3(Y1241~p),PI3K(SH2~u) <-> HER3(Y1241~p!1),PI3K(SH2~rec!1)
    233. 

  233. 'HER3_PI3K#5'HER3(Y1257~p),PI3K(SH2~u) <-> HER3(Y1257~p!1),PI3K(SH2~rec!1)
    234. 

  234. 'HER3_PI3K#6'HER3(Y1270~p),PI3K(SH2~u) <-> HER3(Y1270~p!1),PI3K(SH2~rec!1)
    235. 

  235. 'HER3_Shc'HER3(Y1309~p),Shc(PTB~u) <-> HER3(Y1309~p!1),Shc(PTB~rec!1)
    236. 

  236. 'HER4_RasGAP'HER4(Y1~p),RasGAP(SH2~u) <-> HER4(Y1~p!1),RasGAP(SH2~rec!1)
    237. 

  237. 'HER4_Grb2'HER4(Y2~p),Grb2(SH2~u) <-> HER4(Y2~p!1),Grb2(SH2~rec!1)
    238. 

  238. 'HER4_Shc'HER4(Y3~p),Shc(PTB~u) <-> HER4(Y3~p!1),Shc(PTB~rec!1)
    239. 

  239. 'Shc@Y'Shc(PTB~rec!_,Y~u) -> Shc(PTB~rec!_,Y~p)
    240. 

  240. 'Gab1@48'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y48~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y48~p)
    241. 

  241. 'Gab1@317'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y317~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y317~p)
    242. 

  242. 'Gab1@447'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447~p)
    243. 

  243. 'Gab1@472'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472~p)
    244. 

  244. 'Gab1@619'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619~p)
    245. 

  245. 'Gab1@657'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y657~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y657~p)
    246. 

  246. 'Gab1@689'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y689~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y689~p)
    247. 

  247. 'Gab1@48_op'Gab1(Y48~p) -> Gab1(Y48~u)
    248. 

  248. 'Gab1@317_op'Gab1(Y317~p) -> Gab1(Y317~u)
    249. 

  249. 'Gab1@657_op'Gab1(Y657~p) -> Gab1(Y657~u)
    250. 

  250. 'Gab1@689_op'Gab1(Y689~p) -> Gab1(Y689~u)
    251. 

  251. 'Gab1_Grb2'Gab1(Y48~p),Grb2(SH2) <-> Gab1(Y48~p!1),Grb2(SH2!1)
    252. 

  252. 'Gab1_RasGAP'Gab1(Y317~p),RasGAP(SH2) <-> Gab1(Y317~p!1),RasGAP(SH2!1)
    253. 

  253. 'Gab1_PI3K@447_op'Gab1(Y447!1),PI3K(SH2!1) -> Gab1(Y447),PI3K(SH2)
    254. 

  254. 'Gab1_PI3K@472_op'Gab1(Y472!1),PI3K(SH2!1) -> Gab1(Y472),PI3K(SH2)
    255. 

  255. 'Gab1_PI3K@619_op'Gab1(Y619!1),PI3K(SH2!1) -> Gab1(Y619),PI3K(SH2)
    256. 

  256. 'Gab1_Shp2#1'Gab1(Y689~p),Shp2(SH2c) -> Gab1(Y689~p!1),Shp2(SH2c!1)
    257. 

  257. 'Gab1_Shp2#2'Gab1(Y657~p,Y689!1),Shp2(SH2n,SH2c!1) -> Gab1(Y657~p!2,Y689!1),Shp2(SH2n!2,SH2c!1)
    258. 

  258. 'Gab1_Shp2_op#1'Gab1(Y657!1),Shp2(SH2n!1) -> Gab1(Y657),Shp2(SH2n)
    259. 

  259. 'Gab1_Shp2_op#2'Gab1(Y689!1),Shp2(SH2c!1) -> Gab1(Y689),Shp2(SH2c)
    260. 

  260. 'Rule99'Gab1(Y317~p,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2) -> Gab1(Y317~u,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2)
    261. 

  261. 'Rule100'Gab1(Y447~p,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2) -> Gab1(Y447~u,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2)
    262. 

  262. 'Rule101'Gab1(Y472~p,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2) -> Gab1(Y472~u,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2)
    263. 

  263. 'Rule102'Gab1(Y619~p,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2) -> Gab1(Y619~u,Y657!1,Y689!2),Shp2(SH2n!1,SH2c!2)
    264. 

  264. 'PI3K@s Rec'PI3K(SH2~rec!_,s~u) -> PI3K(SH2~rec!_,s~p)
    265. 

  265. 'PI3K@s Gab#1'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447!2),PI3K(SH2!2,s~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447!2),PI3K(SH2!2,s~p)
    266. 

  266. 'PI3K@s Gab#2'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472!2),PI3K(SH2!2,s~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472!2),PI3K(SH2!2,s~p)
    267. 

  267. 'PI3K@s Gab#3'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619!2),PI3K(SH2!2,s~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619!2),PI3K(SH2!2,s~p)
    268. 

  268. 'PI3K@s_op'PI3K(s~p) -> PI3K(s~u)
    269. 

  269. 'SoS short arm'Grb2(SH2~rec!_,SH3n!1),SoS(PR!1,GEF),Ras(s~gdp) -> Grb2(SH2~rec!_,SH3n!1),SoS(PR!1,GEF!2),Ras(s~gdp!2)
    270. 

  270. 'SoS long arm'Shc(PTB~rec!_,Y!1),Grb2(SH2!1,SH3n!2),SoS(PR!2,GEF),Ras(s~gdp) -> Shc(PTB~rec!_,Y!1),Grb2(SH2!1,SH3n!2),SoS(PR!2,GEF!3),Ras(s~gdp!3)
    271. 

  271. 'SoS vlong arm'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y48!2),Grb2(SH2!2,SH3n!3),SoS(PR!3,GEF),Ras(s~gdp) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y48!2),Grb2(SH2!2,SH3n!3),SoS(PR!3,GEF!4),Ras(s~gdp!4)
    272. 

  272. 'RasGAP no arm'RasGAP(SH2~rec!_,GAP),Ras(s~gtp) -> RasGAP(SH2~rec!_,GAP!1),Ras(s~gtp!1)
    273. 

  273. 'RasGAP long arm'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y317!2),RasGAP(SH2!2,GAP),Ras(s~gtp) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y317!2),RasGAP(SH2!2,GAP!3),Ras(s~gtp!3)
    274. 

  274. 'PI3K no arm'PI3K(SH2~rec!_,s~p),PI(three~u) -> PI3K(SH2~rec!_,s~p!1),PI(three~u!1)
    275. 

  275. 'PI3K long arm #1'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447!2),PI3K(SH2!2,s~p),PI(three~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447!2),PI3K(SH2!2,s~p!3),PI(three~u!3)
    276. 

  276. 'PI3K long arm #2'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472!2),PI3K(SH2!2,s~p),PI(three~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472!2),PI3K(SH2!2,s~p!3),PI(three~u!3)
    277. 

  277. 'PI3K long arm #3'Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619!2),PI3K(SH2!2,s~p),PI(three~u) -> Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619!2),PI3K(SH2!2,s~p!3),PI(three~u!3)
    278. 

  278. 'intrinsic GDP'Ras(s~gtp) -> Ras(s~gdp)
    279. 

  279. 'PI@five'PI(five~u) -> PI(five~p)
    280. 

  280. 'PI@five_op'SHIP(s!1),PI(five~p!1) -> SHIP(s!1),PI(five~u!1)
    281. 

  281. 'Ras_PI3K no arm'Ras(s~gtp),PI3K(SH2~rec!_,RBD,s~u) -> Ras(s~gtp!1),PI3K(SH2~rec!_,RBD!1,s~u)
    282. 

  282. 'Ras_PI3K long arm #1'Ras(s~gtp),Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447!2),PI3K(SH2!2,RBD,s~u) -> Ras(s~gtp!3),Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y447!2),PI3K(SH2!2,RBD!3,s~u)
    283. 

  283. 'Ras_PI3K long arm #2'Ras(s~gtp),Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472!2),PI3K(SH2!2,RBD,s~u) -> Ras(s~gtp!3),Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y472!2),PI3K(SH2!2,RBD!3,s~u)
    284. 

  284. 'Ras_PI3K long arm #3'Ras(s~gtp),Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619!2),PI3K(SH2!2,RBD,s~u) -> Ras(s~gtp!3),Grb2(SH2~rec!_,SH3c!1),Gab1(PR!1,Y619!2),PI3K(SH2!2,RBD!3,s~u)
    285. 

  285. 'Ras_PI3K_op'Ras(s!1),PI3K(RBD!1) -> Ras(s),PI3K(RBD)
    286. 

  286. 'PIP3_Gab1'PI(three~p,four~p,five~p),Grb2(SH2~rec!_,SH3c!1),Gab1(PH,PR!1) -> PI(three~p!2,four~p,five~p),Grb2(SH2~rec!_,SH3c!1),Gab1(PH!2,PR!1)
    287. 

  287. 'PIP3_Gab1_op'PI(three!1),Gab1(PH!1) -> PI(three),Gab1(PH)
    288. 

  288. 'PI3K@s Ras'PI3K(RBD!_,s~u) -> PI3K(RBD!_,s~p)
    289. 

  289. 'RasGAP Gab arm'Gab1(PH!_,Y317~p!1),RasGAP(SH2!1,GAP),Ras(s~gtp) -> Gab1(PH!_,Y317~p!1),RasGAP(SH2!1,GAP!2),Ras(s~gtp!2)
    290. 

  290. 'SoS Gab arm #1'Gab1(PH!_,Y48~p!1),Grb2(SH2!1,SH3n!2),SoS(PR!2,GEF),Ras(s~gdp) -> Gab1(PH!_,Y48~p!1),Grb2(SH2!1,SH3n!2),SoS(PR!2,GEF!3),Ras(s~gdp!3)
    291. 

  291. 'SoS Gab arm #2'Gab1(PH!_,PR!1),Grb2(SH3c!1,SH3n!2),SoS(PR!2,GEF),Ras(s~gdp) -> Gab1(PH!_,PR!1),Grb2(SH3c!1,SH3n!2),SoS(PR!2,GEF!3),Ras(s~gdp!3)
    292. 

  292. 'PI3K Ras arm'PI3K(RBD!_,s~p),PI(three~u) -> PI3K(RBD!_,s~p!1),PI(three~u!1)
    293. 

  293. 'PI3K Gab arm #1'Gab1(PH!_,Y447!1),PI3K(SH2!1,s~p),PI(three~u) -> Gab1(PH!_,Y447!1),PI3K(SH2!1,s~p!2),PI(three~u!2)
    294. 

  294. 'PI3K Gab arm #2'Gab1(PH!_,Y472!1),PI3K(SH2!1,s~p),PI(three~u) -> Gab1(PH!_,Y472!1),PI3K(SH2!1,s~p!2),PI(three~u!2)
    295. 

  295. 'PI3K Gab arm #3'Gab1(PH!_,Y619!1),PI3K(SH2!1,s~p),PI(three~u) -> Gab1(PH!_,Y619!1),PI3K(SH2!1,s~p!2),PI(three~u!2)
    296. 

  296. 'ERK_SoS'ERK(s,T~p,Y~p),SoS(S~u) -> ERK(s!1,T~p,Y~p),SoS(S~u!1)
    297. 

  297. 'ERK_SoS_op'ERK(s!1),SoS(S!1) -> ERK(s),SoS(S)
    298. 

  298. 'ERK_Gab1#1'ERK(s,T~p,Y~p),Gab1(S454~u) -> ERK(s!1,T~p,Y~p),Gab1(S454~u!1)
    299. 

  299. 'ERK_Gab1#2'ERK(s,T~p,Y~p),Gab1(T476~u) -> ERK(s!1,T~p,Y~p),Gab1(T476~u!1)
    300. 

  300. 'ERK_Gab1#3'ERK(s,T~p,Y~p),Gab1(S597~u) -> ERK(s!1,T~p,Y~p),Gab1(S597~u!1)
    301. 

  301. 'ERK_Gab1#1_op'ERK(s!1),Gab1(S454!1) -> ERK(s),Gab1(S454)
    302. 

  302. 'ERK_Gab1#2_op'ERK(s!1),Gab1(T476!1) -> ERK(s),Gab1(T476)
    303. 

  303. 'ERK_Gab1#3_op'ERK(s!1),Gab1(S597!1) -> ERK(s),Gab1(S597)
    304. 

  304. 'SoS@S'ERK(s!1),SoS(S~u!1) -> ERK(s!1),SoS(S~p!1)
    305. 

  305. 'SoS@S_op'SoS(S~p) -> SoS(S~u)
    306. 

  306. 'Gab1@454'ERK(s!1),Gab1(S454~u!1) -> ERK(s!1),Gab1(S454~p!1)
    307. 

  307. 'Gab1@476'ERK(s!1),Gab1(T476~u!1) -> ERK(s!1),Gab1(T476~p!1)
    308. 

  308. 'Gab1@597'ERK(s!1),Gab1(S597~u!1) -> ERK(s!1),Gab1(S597~p!1)
    309. 

  309. 'Gab1@454_op'Gab1(S454~p) -> Gab1(S454~u)
    310. 

  310. 'Gab1@476_op'Gab1(T476~p) -> Gab1(T476~u)
    311. 

  311. 'Gab1@597_op'Gab1(S597~p) -> Gab1(S597~u)
    312. 

  312. 'EGFR_Grb2@Y1086_SH2'EGFR(Y1086~p),Grb2(SH2) -> EGFR(Y1086~p!1),Grb2(SH2!1)
    313. 

  313. 'Shc_Src@SH2_S1'PI(four~p,Five~p!1),Shc(PTB!1,SH2),Src(S1) -> PI(four~p,Five~p!1),Shc(PTB!1,SH2!2),Src(S1!2)
    314. 

  314. 'Shc_p@Y239'PI(four~p,Five~p!1),Shc(PTB!1,SH2,Y239~u),Src(S1) -> PI(four~p,Five~p!1),Shc(PTB!1,SH2!2,Y239~p),Src(S1!2)
    315. 

  315. 'Shc_Src_op'PI(four~p,Five~p!1),Shc(PTB!1,SH2!2,Y239~p),Src(S1!2) -> PI(four~p,Five~p!1),Shc(PTB!1,SH2,Y239~p),Src(S1)
    316. 

  316. 'Shc_p@Y240'PI(four~p,Five~p!1),Shc(PTB!1,SH2,Y240~u),Src(S1) -> PI(four~p,Five~p!1),Shc(PTB!1,SH2!2,Y240~p),Src(S1!2)
    317. 

  317. 'SHP1_EGFR@SH2n_Y1173'Shp1(SH2n),EGFR(Y1173~p) -> Shp1(SH2n!1),EGFR(Y1173~p!1)
    318. 

  318. 'EGFR_u@Y1173'Shp1(SH2n!1),EGFR(Y1173~p!1) -> Shp1(SH2n!1),EGFR(Y1173~u!1)
    319. 

  319. 'EGFR_SHP1_op'Shp1(SH2n!1),EGFR(Y1173~u!1) -> Shp1(SH2n),EGFR(Y1173~u)
    320. 

  320. 'EGFR_Shc@Y1173_PTB'Shc(PTB),EGFR(Y1173~p) -> Shc(PTB!1),EGFR(Y1173~p!1)
    321. 

  321. 'EGFR_Shc@Y1173_SH2'Shc(SH2),EGFR(Y1173~p) -> Shc(SH2!1),EGFR(Y1173~p!1)
    322. 

  322. 'EGFR_Shc@Y992_PTB'Shc(PTB),EGFR(Y992~p) -> Shc(PTB!1),EGFR(Y992~p!1)
    323. 

  323. 'EGFR_Shc@Y992_SH2'Shc(SH2),EGFR(Y992~p) -> Shc(SH2!1),EGFR(Y992~p!1)
    324. 

  324. 'Shc_EGFR@PTB_Y1148'EGFR(Y1148~p),Shc(PTB) <-> EGFR(Y1148~p!1),Shc(PTB!1)
    325. 

  325. 'Shc_EGFR@SH2_Y1148'EGFR(Y1148~p),Shc(SH2) <-> EGFR(Y1148~p!1),Shc(SH2!1)
    326. 

  326. 'Shc_EGFR@PTB_Y1173'EGFR(Y1173~p),Shc(PTB) <-> EGFR(Y1173~p!1),Shc(PTB!1)
    327. 

  327. 'Shc_EGFR@SH2_Y1173'EGFR(Y1173~p),Shc(SH2) <-> EGFR(Y1173~p!1),Shc(SH2!1)
    328. 

  328. 'Shc_p@Y317'EGFR(Y1148~p!1),Shc(PTB!1,Y317~u) -> EGFR(Y1148~p!1),Shc(PTB!1,Y317~p)
    329. 

  329. 'EGFR_Stat3@Y1068_SH2'Stat3(SH2),EGFR(Y1068~p) <-> Stat3(SH2!1),EGFR(Y1068~p!1)
    330. 

  330. 'EGFR_Stat3@Y1086_SH2'Stat3(SH2),EGFR(Y1086~p) <-> Stat3(SH2!1),EGFR(Y1086~p!1)
    331. 

  331. 'Stat3_p@Y705'Stat3(SH2!1,Y705~u),EGFR(Y1068!1) -> Stat3(SH2!1,Y705~p),EGFR(Y1068!1)
    332. 

  332. 'EGFR_Shc@Y1068_SH2'EGFR(Y1068~p),Shc(SH2) <-> EGFR(Y1068~p!1),Shc(SH2!1)
    333. 

  333. 'EGFR_Shc@Y1086_SH2'EGFR(Y1086~p),Shc(SH2) <-> EGFR(Y1086~p!1),Shc(SH2!1)
    334. 

  334. 'EGFR_PLCG1@Y992_SH2'EGFR(Y992~p),PLCG1(SH2) <-> EGFR(Y992~p!1),PLCG1(SH2!1)
    335. 

  335. 'EGFR_PLCG1@Y1068_SH2'EGFR(Y1068~p),PLCG1(SH2) <-> EGFR(Y1068~p!1),PLCG1(SH2!1)
    336. 

  336. 'EGFR_PLCG1@Y1086_SH2'EGFR(Y1086~p),PLCG1(SH2) <-> EGFR(Y1086~p!1),PLCG1(SH2!1)
    337. 

  337. 'EGFR_PLCG1@Y1148_SH2'EGFR(Y1148~p),PLCG1(SH2) <-> EGFR(Y1148~p!1),PLCG1(SH2!1)
    338. 

  338. 'EGFR_PLCG1@Y1173_SH2'EGFR(Y1173~p),PLCG1(SH2) <-> EGFR(Y1173~p!1),PLCG1(SH2!1)
    339. 

  339. 'EGFR_Src@Y845_SH2'Src(SH2),EGFR(Y845) <-> Src(SH2!1),EGFR(Y845!1)
    340. 

  340. 'EGFR_p@Y845'Src(SH2!1),EGFR(Y845~u!1) -> Src(SH2!1),EGFR(Y845~p!1)
    341. 

  341. 'EGFR_Eps8@S1_S1'EGFR(S1),Eps8(S1) <-> EGFR(S1!1),Eps8(S1!1)
    342. 

  342. 'Eps8_p@X'EGFR(S1!1),Eps8(S1!1,X~u) -> EGFR(S1!1),Eps8(S1!1,X~p)
    343. 

  343. 'EGFR_PLCG1@Y1173_SH2n'EGFR(Y1173~p),PLCG1(SH2n) -> EGFR(Y1173~p!1),PLCG1(SH2n!1)
    344. 

  344. 'EGFR_PLCG1@Y992_SH2c'EGFR(Y992~p),PLCG1(SH2c) -> EGFR(Y992~p!2),PLCG1(SH2c!2)
    345. 

  345. 'PLCG1_p@Y472'EGFR(Y1173~p!1),PLCG1(SH2n!1,Y472~u) -> EGFR(Y1173~p!1),PLCG1(SH2n!1,Y472~p)
    346. 

  346. 'PLCG1_p@Y771'EGFR(Y1173~p!1),PLCG1(SH2n!1,Y771~u) -> EGFR(Y1173~p!1),PLCG1(SH2n!1,Y771~p)
    347. 

  347. 'PLCG1_p@Y783'EGFR(Y1173~p!1),PLCG1(SH2n!1,Y783~u) -> EGFR(Y1173~p!1),PLCG1(SH2n!1,Y783~p)
    348. 

  348. 'PLCG1_p@Y1254'EGFR(Y1173~p!1),PLCG1(SH2n!1,Y1254~u) -> EGFR(Y1173~p!1),PLCG1(SH2n!1,Y1254~p)
    349. 

  349. 'EGFR_Gab1@S1_S1'Gab1(X~u),EGFR(S1) -> Gab1(X~u!1),EGFR(S1!1)
    350. 

  350. 'Gab1_p@Y627'Gab1(Y627~u!1),EGFR(S1!1) -> Gab1(Y627~p!1),EGFR(S1!1)
    351. 

  351. 'Gab1_EGFR_op'Gab1(Y627~p!1),EGFR(S1!1) -> Gab1(Y627~p),EGFR(S1)
    352. 

  352. 'Gab1_p@Y659'Gab1(Y659~u!1),EGFR(S1!1) -> Gab1(Y659~p!1),EGFR(S1!1)
    353. 

  353. 'Gab1_PIP3@PH'Gab1(PH),PI(three~p,four~p,five~p) -> Gab1(PH!1),PI(three~p,four~p,five~p!1)
    354. 

  354. 'Gab1_SHP2@Y627_SH2n'Gab1(Y627~p),SHP2(SH2n) -> Gab1(Y627~p!1),SHP2(SH2n!1)
    355. 

  355. 'Gab1_SHP2@Y659_SH2c'Gab1(Y659~p),SHP2(SH2c) -> Gab1(Y659~p!1),SHP2(SH2c!1)
    356. 

  356. 'Gab1_u@Y659'Gab1(Y659~p!1),SHP2(SH2c!1) -> Gab1(Y659~u!1),SHP2(SH2c!1)
    357. 

  357. 'Gab1_u@Y627'Gab1(Y627~p!1),SHP2(SH2c!1) -> Gab1(Y627~u!1),SHP2(SH2c!1)
    358. 

  358. 'Gab1_PLCG1@Y307_SH2'Gab1(Y307~p),PLCG1(SH2) -> Gab1(Y307~p!1),PLCG1(SH2!1)
    359. 

  359. 'Gab1_PLCG1@Y373_SH2'Gab1(Y373~p),PLCG1(SH2) -> Gab1(Y373~p!1),PLCG1(SH2!1)
    360. 

  360. 'Gab1_PLCG1@Y407_SH2'Gab1(Y407~p),PLCG1(SH2) -> Gab1(Y407~p!1),PLCG1(SH2!1)
    361. 

  361. 'Akt_PIP2@PH'Akt(PH),PI(three~p,four~p) -> Akt(PH!1),PI(three~p,four~p!1)
    362. 

  362. 'Vav_PIP3@PH'PI(three~p,four~p,five~p),Vav(PH) <-> PI(three~p,four~p,five~p!1),Vav(PH!1)
    363. 

  363. 'Vav_Rac@DH_X~u'PI(three~p,four~p,five~p!1),Vav(PH!1,DH,X~p),Rac(X~u) <-> PI(three~p,four~p,five~p!1),Vav(PH!1,DH!2,X~p),Rac(X~u!2)
    364. 

  364. 'Rac_p@X'Rac(X~gdp!1),Vav(DH!1,PH!2,X~p),PI(three~p,four~p,five~p!2) -> Rac(X~gtp!1),Vav(DH!1,PH!2,X~p),PI(three~p,four~p,five~p!2)
    365. 

  365. 'PIP3_Sos@PH'PI(three~p,four~p,five~p),Sos(PH) -> PI(three~p,four~p,five~p!1),Sos(PH!1)
    366. 

  366. 'Sos_Rac@DH_X~u'PI(three~p,four~p,five~p!1),Sos(PH!1,DH,X~p),Rac(X~u) <-> PI(three~p,four~p,five~p!1),Sos(PH!1,DH!2,X~p),Rac(X~u!2)
    367. 

  367. 'PIP2_PLD@PH'PI(four~p,five~p),PLD(PH) <-> PI(four~p,five~p!1),PLD(PH!1)
    368. 

  368. 'p85_EGFR@SH2_Y920'p85(SH2),EGFR(Y920~p) -> p85(SH2!1),EGFR(Y920~p!1)
    369. 

  369. 'Rom2_PI3K@PH_S1'Rom2(PH),PI3K(S1) <-> Rom2(PH!1),PI3K(S1!1)
    370. 

  370. 'EGFR_Vav2@Y992_SH2'EGFR(Y992~p),Vav2(SH2) <-> EGFR(Y992~p!1),Vav2(SH2!1)
    371. 

  371. 'EGFR_Vav@Y1148_SH2'EGFR(Y1148~p),Vav2(SH2) <-> EGFR(Y1148~p!1),Vav2(SH2!1)
    372. 

  372. 'Vav2_p@Y142'EGFR(Y1148~p!1),Vav2(SH2!1,Y142~u) -> EGFR(Y1148~p!1),Vav2(SH2!1,Y142~p)
    373. 

  373. 'Vav2_p@Y172'EGFR(Y1148~p!1),Vav2(SH2!1,Y172~u) -> EGFR(Y1148~p!1),Vav2(SH2!1,Y172~p)
    374. 

  374. 'Vav2_p@Y159'EGFR(Y1148~p!1),Vav2(SH2!1,Y159~u) -> EGFR(Y1148~p!1),Vav2(SH2!1,Y159~p)
    375. 

  375. 'Grb2_EGFR@SH2_Y1068'Grb2(SH2),EGFR(Y1068~p) -> Grb2(SH2!1),EGFR(Y1068~p!1)
    376. 

  376. 'Pak1_Grb2@SH3_SBM'Grb2(SH2!1,SH3),EGFR(Y1068~p!1),Pak1(SBM) -> Grb2(SH2!1,SH3!2),EGFR(Y1068~p!1),Pak1(SBM!2)
    377. 

  377. 'Raf1_Ras@CR1_rafts'Raf1(Y341~p,CR1),Ras(rafts) -> Raf1(Y341~p,CR1!1),Ras(rafts!1)
    378. 

  378. 'Raf1_p@S338'Raf1(Y341~p,CR1!1,S338~u),Ras(rafts!1) -> Raf1(Y341~p,CR1!1,S338~p),Ras(rafts!1)
    379. 

  379. 'Ang2_EGFR@r_l'Ang2(r~ext),EGFR(L~ext,CR) <-> Ang(r~ext!1),GFR(L~ext!1,CR)
    380. 

  380. 'EGFR_Clta(int)'EGFR(N~ext!1,C),CLTA(S1!1) -> EGFR(N~int!1,C),CLTA(S1!1)
    381. 

  381. 'Rule103'B(y1~p) -> B(y1~u)
    382. 

  382. 'Rule104'B(y2~p) -> B(y2~u)
    383. 

  383. 'goal'B(y1~p,y2~p,z~u) -> B(y1~p,y2~p,z~p)
    384. 

  384. 'Rule105'ErbB2(N!1,bp!2),ErbB1(C!1,Y1148~u),A(s~ppp!2) -> ErbB2(N!1,bp!2),ErbB1(C!1,Y1148~p),A(s~pp!2)
    385.